Applying muscle forces to finite element models of bone How much modeling precision is necessary

DUMONT, E.R.*; GROSSE, I.R.; COLETTA, C.E.; UMass, Amherst; UMass, Amherst; UMass, Amherst: Applying muscle forces to finite element models of bone: How much modeling precision is necessary? Finite element analysis (FEA) is a powerful tool for understanding the mechanics of physical systems. Existing FEA tools were developed to enable engineers to predict the physical behavior […]

An investigation into the effects of PCB 126 on bone density in turtles

FORD, D.K.*; HOLLIDAY, C.M.; Ohio University, Athens, OH; Ohio University, Athens, OH: An investigation into the effects of PCB 126 on bone density in turtles Bone is a metabolically active tissue functioning as a physiological mineral reservoir while also providing support and defense for the organism. However, the physical properties of skeletal tissues may be […]

Understanding hypoxia-induced gene expression in early development In vitro and in vivo analysis of HIF-1-regulated zebrafish IGFBP-1 gene expression

KAJIMURA, S.*; AIDA, K.; DUAN, C.; University of Michigan, Ann Arbor; University of Tokyo, Tokyo; University of Michigan, Ann Arbor: Understanding hypoxia-induced gene expression in early development: In vitro and in vivo analysis of HIF-1-regulated zebrafish IGFBP-1 gene expression Insulin-like growth factor binding protein-1 (IGFBP-1) is a hypoxia-inducible gene. Previous studies have shown that the […]

Ovarian Response to Gonadotropin in Alligator Neonates

MOORE, Brandon C*; COOK, Robert W; CHUNG, Koo Whang; ALVERS, Ashley L; WOODRUFF, Teresa K; GUILLETTE, Louis J; University of Florida, Gainesville; Northwestern University, Evanston; University of Florida, Gainesville; University of Florida, Gainesville; Northwestern University, Evanston; University of Florida, Gainesville: Ovarian Response to Gonadotropin in Alligator Neonates Ovarian folliculogenesis is a fundamental process of ovarian […]

Nutritional Regulation of the Somatotropic Axis of Rainbow Trout (Oncorhynchus mykiss)

NORBECK, L.; KITTILSON, J.; SHERIDAN, M.A.*; North Dakota State University, Fargo.; North Dakota State University, Fargo.; North Dakota State University, Fargo.: Nutritional Regulation of the Somatotropic Axis of Rainbow Trout (Oncorhynchus mykiss). Previously, we isolated and characterized the mRNAs that encode for major elements of the somatotropic axis of rainbow trout, including two forms of […]

Investigation of the causal gene underlying a quantitative trait locus (QTL) contributing to genetic variation in growth

CHRISTIANS, Julian K*; HOEFLICH, Andreas; KEIGHTLEY, Peter D; Simon Fraser University; Ludwig-Maximilians Universitaet; University of Edinburgh: Investigation of the causal gene underlying a quantitative trait locus (QTL) contributing to genetic variation in growth Within all species, many traits show continuous variation between individuals, with phenotype determined by both the environment and a potentially large number […]

Gene-specific changes in promoter occupancy by thyroid hormone receptor during frog metamorphosis Implications for developmental gene regulation

BUCHHOLZ, D.R.*; PAUL, B.P.; SHI, Y.-B.; Laboratory of Gene Regulation, National Institute of Child Health and Human Development: Gene-specific changes in promoter occupancy by thyroid hormone receptor during frog metamorphosis: Implications for developmental gene regulation In all vertebrates, thyroid hormones (TH) affect post-embryonic developmental processes. The role of TH receptor (TR) in mediating the TH […]

Endothelin receptors in the killifish, Fundulus heteroclitus, gill

HYNDMAN, K/A*; EVANS, D/H; University of Florida, Gainesville; University of Florida, Gainesville: Endothelin receptors in the killifish, Fundulus heteroclitus, gill The endothelin (ET) signaling cascade is traditionally viewed as three paracrines, ET-1, ET-2 and ET-3 that bind to two membrane bound receptors, ETA and ETB. Generally, when ETs bind to receptors on vascular smooth muscle […]

Characterization of an ancestral type II GnRH receptor function and pharmacological profile of the sea lamprey GnRH receptor

SILVER, M.R.*; SOWER, S.A.; University of New Hampshire; University of New Hampshire: Characterization of an ancestral type II GnRH receptor: function and pharmacological profile of the sea lamprey GnRH receptor Neuroendocrine regulation of reproduction in vertebrates is regulated by gonadotropin-releasing hormone (GnRH). GnRH acts on gonadotropes located in the anterior pituitary via its receptor, a […]

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