FORREST, T.G.; University of North Carolina at Asheville: Behavioral ecology of a non-flashing firefly During a two-season study of a Phausis inaccensa population, I tracked the mating history, temporal distribution and spatial distribution of more than 150 females. Phausis inaccensa exhibits the ‘primitive’ condition in firefly communication systems. Flightless larviform females emerge from burrows shortly […]

MCCORMICK, Stephen D.; HIROI, Junya; USGS, Conte Anadromous Fish Research Center, Turners Falls, MA, USA: The effect of salinity on CFTR, NKCC, and Na,K-ATPase in gill chloride cells of teleost fish. The localization, quantitation and effect of salinity on the cystic fibrosis transmembrane regulator (CFTR), Na,K,2Cl cotransporter (NKCC) and sodium pump (Na,K-ATPase) were examined in […]

BEAR, C.E., E; LI, C., ; KIDD, J.F., ; KOGAN, I., ; HUAN, L.-J., ; RAMJEESINGH, M., ; Hospital for Sick Children, Toronto, Canada: Quaternary structure of CFTR and putative intramolecular interactions may mediate CFTR function CFTR is a member of the ABC superfamily of transport ATPases. Recent high resolution structures of intact procaryotic transporters […]

HANRAHAN, J.W.; HINKSON, D.A.R.; EVAGELIDIS, A.; LUO, Y.; RIORDAN, J.R.; CHANG, X.-B. *more*; McGill Univ.; McGill Univ.; McGill Univ.; McGill Univ.; Mayo Clinic Scottsdale; Mayo Clinic Scottsdale *more*: PHOSPHORYLATION CONTROL OF CFTR CHANNEL ACTIVITY AND DOMAIN-DOMAIN INTERACTIONS CFTR is controlled by its regulatory or �R� domain, which has many consensus sequences for phosphorylation by PKA […]

SINGER, T.D.*; SCHULTE, P.M.; University of Waterloo*; University of British Columbia: Osmoregulation and control of CFTR expression in teleost fish Homologues of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) play an important role in osmoregulation of seawater adapted teleost fish. CFTR, an apically located chloride channel, interacts with basolaterally located Na+,K+-ATPase and a Na+K+2Cl– co-transporter […]

LARSEN, E. H.*; AMSTRUP, J.; WILLUMSEN, N.J.; University of Copenhagen, Denmark: Function, regulation and cloning of CFTR in toad (Bufo bufo) skin mitochondria rich cells Amphibian skin absorbs NaCl and H2O by epidermal cells and secretes fluid by subepidermal glands. CFTR is implicated in both functions. The epidermis contains Na transporting principal cells and Cl […]

SCHULTE, P.M.*; SINGER, T.D.; Univ. of British Columbia; Univ. of Waterloo: Comparative genomic sequence analysis of CFTR The cystic fibrosis transmembrane conductance regulator (CFTR) has a highly regulated expression pattern, but the sequences regulating its transcription remain poorly characterized. We have used a genomics approach (phylogenetic footprinting) to characterize regulatory elements involved in CFTR expression. […]

MARSHALL, W.S.; LYNCH, E.M.; HOWARD, J.A.; EPEGA, A.; COZZI, R.R.F.; St. Francis Xavier U.: CFTR expression patterns in a euryhaline teleost fish. Cystic Fibrosis Transmembrane conductance Regulator (CFTR) in the euryhaline killifish Fundulus heteroclitus (kfCFTR) is an anion channel expressed in gill, opercular epithelium, brain and intestine. We established that CFTR was the channel responsible […]

CUTLER, C.; CRAMB, G.; Univ. of St Andrews, UK: A comparative analysis of CFTR in teleost fish. The cloning of CFTR cDNA sequences from a number of teleost species allows an analysis of both sequence and expression data to be performed. Analysis of teleost CFTR sequences shows, that as a group,teleost CFTR orthologues are approximately […]

IRSCHICK, DUNCAN J.*; Tulane University: Studying performance in nature: Implications for fitness variation within populations Many biologists believe that the ability of an organism to survive in nature is influenced by key performance traits, such as maximum speed. Studies of ecological performance (the level of performance exhibited in nature) can thus provide general insight into […]