JOHN-ALDER, H.B.*; HAENEL, G.J.: Experimental and Demographic Analyses of Growth and Sexual Size Dimorphism in a Lizard, Sceloporus undulatus Sexual size dimorphism (SSD) is a common phenomenon caused by a variety of environmental and genetic mechanisms in animals. In the current study, we investigate the demography of a population of eastern fence lizards (Sceloporus undulatus) […]

D’AMICO, L.J.*; DAVIDOWITZ, G.; NIJHOUT, H.F.: Body size evolution in a laboratory strain of Manduca sexta : Implications for studies in insect physiology and endocrinology The tobacco hornworm, Manduca sexta, has been used as a model organism for the study of insect developmental physiology and endocrinology for more than 30 years. Many of the connections […]

MAURES, TJ; ROYER, T; DUAN, C: Structure, developmental expression, and physiological regulation of zebrafish insulin-like growth factor binding protein-1 In this study, we have cloned and characterized the full-length insulin-like growth factor binding protein-1 (IGFBP-1) cDNA from zebrafish. The full-length 1032 bp cDNA encodes a protein of 283 amino acids. The 263 residue mature zebrafish […]

SHIMIZU, M.*; SWANSON, P.; HARA, A.; DICKHOFF, W.W.: Purification of a serum insulin-like growth factor binding protein from chinook salmon, Oncorhynchus tshawytscha Circulating insulin-like growth factors (IGFs) are bound to multiple binding proteins. IGF-binding proteins (IGFBPs ) modulate biological activities of IGFs by controlling availability of IGFs to their receptors. In salmon, at least three […]

DURICA, D.S.; WU, X.; HOPKINS, P.M.: Protein-Protein and DNA Binding Properties of a Crustacean Ecdysteroid Receptor. To facilitate physical characterization of their binding properties, we have cloned into expression vectors the entire coding regions of the two components of the Uca pugilator ecdysteroid receptor homolog, UpEcR (Genbank AF034086) and UpRXR (GenBank AF32983). GST-pull down experiments […]

SCHMIDT, KE; DESAI, P; SAK, KM; BALOGH, LM; KELLEY, KM: Membrane Binding of an Insulin-like Growth Factor (IGF)-binding Protein (IGFBP) in a Reptilian Heart Cell: Impact on IGF-I Action A heart cell line (IgH2) derived from Iguana iguana secretes a 30-kDa IGFBP that also localizes to the cell membranes. Competition binding assays on soluble iguana […]

DING, J; DUAN, C: Looking at IGF binding protein-2 actions through the zebrafish eyes Insulin-like growth factors (IGFs) are evolutionarily conserved peptides that are essential for normal animal growth. Recent studies utilizing cell cultures suggest that the bioactivity of IGFs could be modulated by specific, high-affinity IGF-binding proteins (IGFBPs). The in vivo roles of these […]

BERG, LK; DESAI, P; AROPE, SA; KELLEY, KM: Insulin-like Growth Factor-binding Protein-2 (IGFBP-2) and Angiotensin II (AngII) in Glucose-activated Murine Kidney Mesangial Cells With high ambient glucose (e.g., in diabetes), glomerular mesangial cells show activated proliferation and an over-production/accumulation of extracellular matrix (ECM). These changes lead to impaired glomerular filtration and renal failure. Associated changes […]

GUGLIELMO, CG*; PRICE, ER; HAYS, QR; Univ. of Montana; Univ. of Montana; Univ. of Montana: The effects of diet macronutrient composition on fuel selection during exercise in a migratory bird Dendroica coronata In mammals diet macronutrient composition affects exercise fuel utilization and endurance performance. High carbohydrate diets used by marathon athletes enhance glycogen utilization, high […]

JOYNER-MATOS, J.L.*; DOWNS, C.A.; JULIAN, D.; Univ. of Florida; EnVirtue Biotechnologies, Inc.; Univ. of Florida: Stress Protein Expression in the Surf Clam Donax variabilis Following Exposure to Normoxia, Hypoxia, Hyperoxia, and Hydrogen Sulfide. The endogenous production of oxygen-centered free radicals and resulting oxidative damage may occur in tissues exposed to hypoxia, hyperoxia, or hydrogen sulfide. […]