Studies of the role of protein trafficking on collagen fibril assembly in tendon

CANTY, E.G.*; KADLER, K.E.: Studies of the role of protein trafficking on collagen fibril assembly in tendon. Tendon morphogenesis requires the formation of an extracellular matrix (ECM) containing collagen fibrils. How embryonic tendon fibroblasts achieve this elaborate organisation is unknown. We have shown that tendon fibroblasts synthesise ~1 um long early collagen fibrils that fuse […]

Structure-function considerations of muscle-tendon junctions

TROTTER, John A: Structure-function considerations of muscle-tendon junctions. Skeletal muscle fibers transmit force across the cell membrane to the extracellular matrix and ultimately to tendons. Force transmission may occur both along the lateral surfaces of muscle fibers and at their ends. Sites of force-transmission are morphologically and compositionally specialized for this function. They are also […]

Structure and Function of Normally Mineralizing Avian Tendons

LANDIS, W.J.*; SILVER, F.H.: Structure and Function of Normally Mineralizing Avian Tendons Leg tendons of some avians normally calcify. The gastrocnemius tendon of the domestic turkey, Meleagris gallopavo, is an example. Its structure and biomechanical properties have been examined to model the adaptive nature of tendon to external forces, including the means of mineral deposition […]

Structure and Function of Axial Tendons in Tunas

SHADWICK, R.E.: . Structure and Function of Axial Tendons in Tunas. The great lateral tendons in tunas and some other scombrid fish link mytotomal muscle directly to the caudal fin rays, and thus serve to transfer muscle power to the hydrofoil-like tail during swimming. These robust collagenous tendons have structural and mechanical similarity to tendons […]

Myoseptal tendons in vertebrates Spatial arrangement, functional and evolutionary implications

GEMBALLA, Sven: Myoseptal tendons in vertebrates: Spatial arrangement, functional and evolutionary implications A comparative study of myosepta was carried out considering representatives of the major gnathostome taxa (chondrichthyans, actinopterygians, sarcopterygians, urodelans). Tendinous structures embedded in myosepta were detected using a modified clearing and staining technique, dissection of complete septa and light- DIC- and SEM- microscopy. […]

Muscle design features of the equine suspensory ligament

SOFFLER, C.; STORCK, K.I.; HERMANSON, J.W.*: Muscle design features of the equine suspensory ligament. The equine interosseus muscle (“suspensory ligament”) spans the fetlock joint of the forelimb and has been ascribed various functions and morphologic attributes. It stabilizes and prevents overextension of the fetlock. But, the muscle has been variously described as being void of […]

Effects of Exercise on the Biomechanical Properties of Tendon

BUCHANAN, C.I.; MARSH, R.L.: Effects of Exercise on the Biomechanical Properties of Tendon. Tendon has been shown to undergo remodeling in response to strength or endurance training, however, compared to muscle, studies of the effects of exercise on tendon are quite limited. Biomechanical parameters that may change in response to exercise are tensile strength, stiffness […]

Cell Fate Determination and Patterning of Vertebrate Tendons

SCHWEITZER, R.: Cell Fate Determination and Patterning of Vertebrate Tendons Surprisingly little in known about the differentiation on patterning of vertebrate tendons, largely due to the absence of a good molecular marker for this tissue. We have recently demonstrated that Scleraxis, a bHLH transcription factor, is a specific marker for tendons. Scleraxis is expressed in […]

Biomechanics of hypaxial myosepta in swimming salamanders

AZIZI, E.; BRAINERD, E.L.: Biomechanics of hypaxial myosepta in swimming salamanders In contrast to the complex three dimensional shape of myomeres in teleost fishes, the lateral hypaxial muscles of salamanders are nearly planar and their myosepta run in a roughly straight line from mid-lateral to ventral. We used this relatively simple system as the basis […]

Axial Tendons in Fish How do Tensile Structures Create Beam-Like Behavior

LONG, JR, J.H.; ADCOCK, B.; ROOT, R.G.: Axial Tendons in Fish: How do Tensile Structures Create Beam-Like Behavior? Recent work on the in vivo strain of red and white muscle has shown that the swimming fish body bends like a homogenous, continuous beam. This is surprising in light of the body�s heterogeneous tendon and connective […]

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