Interaction of BHT with BPS in Planaria


Meeting Abstract

P2-36  Friday, Jan. 5 15:30 – 17:30  Interaction of BHT with BPS in Planaria CHABRIA, T*; MASSENA, K; FUNK, A; DANISEWICZ, E; THOM, Z; MASS, S; State University of New York at New Paltz; State University of New York at New Paltz; State University of New York at New Paltz; State University of New York at New Paltz; State University of New York at New Paltz; State University of New York at New Paltz chabriat1@hawkmail.newpaltz.edu

Bisphenol compounds such as BPS are environmental endocrine disruptors that act as xenoestrogens. BPS is commonly used to make certain types of plastics and epoxy resins that are used in food packaging, thermal printing and a variety of other consumer and industrial products, and is commonly substituted for BPA in “BPA-free” products. Prior work in our lab has demonstrated that moderate to high doses of BPS adversely affect regeneration in flatworms. Common antioxidants like Butylated-hydroxytoluene (BHT) that are used as preservatives in foods and cosmetics have been coming under renewed scrutiny as potential endocrine disruptors and carcinogens. In this work, we examine the effects of co-administration of BHT with BPS at doses below the LC50 for BPS.

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