The avian lumbosacral spinal cord has several distinctive morphological features that are collectively referred to as the lumbosacral organ (LSO). The LSO is hypothesized to serve as a second set of balance sensors, in addition to those in the inner ear. A few different mechanosensory mechanisms have been proposed for the LSO, including that deformation of the neural tissue or motion of cerebrospinal fluid stimulates sensory neurons within the spinal cord. To design effective experiments to distinguish among mechanosensory functional hypotheses, a deep understanding of the underlying neuroanatomy is required. Here, we present a preliminary immunohistochemical characterization of the LSO region of the avian spinal cord, with a focus on exploring sensory-related attributes. One notable finding is the presence of Myosin VIIa (Myo7a) immunoreactivity in cells near the central canal and the laterally-protruding accessory lobes. Another is the presence of Calcitonin gene-related peptide (CGRP) immunoreactive fibers that invade the dorsally-located glycogen body. Myo7a is associated with mechanosensory function in the hair cells of the inner ear, while CGRP in the dorsal horn is expressed in sensory afferent neurons. We discuss potential mechanosensory implications of these findings in the context of the overarching hypothesis that the avian LSO helps birds balance.