Meeting Abstract
Severe environments can affect the survival of individuals. Survivors could be a random genetic sample of the population or could represent selectively resistant genotypes. This study examined the effect of severe hypoxia on genome wide genetic variation in the teleost fish Fundulus heteroclitus. Two hundred and forty individuals were exposed to hypoxia that resulted in 43 survivors (18% survivorship). Using genotyping-by-sequencing we determined nucleotide divergence in the hypoxic survivors relative to the parental population. For approximately 12,000 single nucleotide polymorphisms (SNPs), 125 SNPs were evolutionarily significant after multiple test correction (p <0.01, 0.01 FDR). These data suggests that exposure to severe hypoxic selects for specific genotypes.