Dogs (Canis familiaris) are an ideal model for inter-disciplinary science. From their beginnings, the evolutionary history of dogs contains unpredicted effects across all levels of biological organization. These include diversification from highly social, pack-dwelling wild carnivores (extant grey wolves), to increased dependence on humans (domestication), and modern colonization our homes and our beds (inter-species bonding). The history and global abundance of this single species provides a rich interdisciplinary opportunity for research. This young, emerging field of “canine science” is comprised of diverse biological disciplines including evolution, genetics, physiology, cognition, behavior, and ecology, drawing on studies of both natural and experimental systems and scaling across all levels of biological organization, from genomes to ecosystems. However, limited connections bridge the various fields associated with canine science and there has been a growing interest over the past few years to integrate the insights from genomic evolution with those from ecophysiology and ecology to gain a more biologically-comprehensive perspective of this species. In particular, canine research that is integrative, mechanistic, and/or ecological in nature has been generally underrepresented. To address these developing interests in the community, this symposium will bring together scientists working in diverse realms of canine research to address noteworthy topics in dog biology. The speakers include experts in dog evolution, genetics, cognition, and physiological ecology. By presenting this combination of expertise, we hope to inform the community of the importance of canine biology, foster collaborations across diverse disciplines, rethink familiar themes, and develop new and tools for canine research so as to collaboratively advance this field.