Meeting Abstract

46.4  Monday, Jan. 5  Acute Effects of Triclosan and Triclocarban Exposure on the Physiology of Four Tadpole Species PALENSKE, N.M.*; DZIALOWSKI, E.M.; University of North Texas, Denton; University of North Texas, Denton npalenske@unt.edu

The goal of this study was to determine acute effects of triclosan (TCS) and triclocarban (TCC), antimicrobials used in consumer products, on the development and physiology of four tadpole species. Acris crepitans blanchardi, Rana sphenocephala, and Bufo woodhousii woodhousii were collected locally in Denton and Tarrant County, Texas and Xenopus laevis was obtained from a commercial supplier. LC50 values were determined for TCS and TCC during Gosner stage 30 for native species and Nieuwkoop and Faber stage 41 for X. laevis. Heart rate and metabolic differences were also examined after 96 hour exposure to TCS and TCC. Nominal LC50 dilutions were used to determine LC50 values for TCS and TCC. A significant difference in LC50 concentration of both TCS and TCC was found between species. A significant increase in heart rate was observed with exposure to TCS, while exposure to TCC caused a significant decrease in heart rate. Metabolic rates of tadpoles exposed to TCS showed significant decreases only in R. sphenocephala and X. laevis. Exposure to TCC caused a significant decrease in metabolic rates of X. laevis. This study indicates that the toxicity of TCS and TCC in tadpoles is dependent upon species.