SICB Division of Comparative Biomechanics (DCB)

DCB Researchers Database Entry

Linda Holland

Amphioxus as the best available stand-in for the ancestral vertebrate
My laboratory focuses on genes and development of the cephalochordate amphioxus and has played a major role in the effort to sequence the amphioxus genome. Annotation will begin in Jan. 2006 and the complete genome is expected to be released by mid-year. On-going projects include evolution of gene regulation and the roles of retinoic acid and wingless signaling pathways in axial patterning.
http://hollandlab.ucsd.edu/intro.htm